By M. Sahay
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We will successively describe the markers which are still used in clinical practice in 2011: inulin, 51Cr-EDTA, 99TcDTPA, iothalamate and iohexol. For every marker, we will describe strengths and limitations both from an analytical and clinical point of view. 3. Inulin Inulin is still considered nowadays as the gold standard to measure GFR. Smith has deeply studied this marker and makes it the most popular. Inulin is a polymer of fructose which is found in some plants which uses it as energy provider in place of amidon.
1969). , 2009). , 1973). , 1997). Iothalamate can yet be measured by “cold” non-isotopic methods. , 1975). This author used fluorescent excitation analysis or X ray fluorescence (XRF), which will be also used for iohexol measurement (see below). In this technique, iodine atoms are ionized by americanum. , 1975). Guesry found an excellent correlation between isotopic and XRF iothalamate measurement. , 1997). The most used methods to measure iothalamate are HPLC methods (Boschi & Marchesini, 1981).
1995). Fallacy of indexing renal and systemic hemodynamic measurements for body surface area. R978-88, ISSN 0002-9513 van der Sijs, H. J. (2002). Formulas for calculating body surface area. ; De Backer, W. & Van Gaal, L. (2006). Body surface area in normal-weight, overweight, and obese adults. A comparison study. 515-524, ISSN 0026-0495 Walser, M. (1990). Progression of chronic renal failure in man. J. J. (1991). Normalisation of glomerular filtration rate measurements. H. H. (2010). Human body surface area database and estimation formula.