Download Amenorrhea: A Case-Based, Clinical Guide by Cary Dicken, Marie Menke, Genevieve Neal-Perry (auth.), PDF

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By Cary Dicken, Marie Menke, Genevieve Neal-Perry (auth.), Nanette F. Santoro, Genevieve Neal-Perry (eds.)

Amenorrhea: A Case-Based scientific advisor is a complete overview of the present wisdom relating to common woman reproductive body structure. Replete with fascinating case vignettes and offering diagnostic algorithms and healing ideas for amenorrhea, Amenorrhea: A Case-Based medical consultant is split into 3 sections. the 1st part consists of 2 chapters that supply an intensive overview of easy technological know-how and medical wisdom concerning the organ structures answerable for common body structure of the menstrual cycle. the second one part contains dialogue approximately menstrual cycle disruption because it pertains to hypothalamic-pituitary disorder, surgical and common menopause, genetic defects, untimely ovarian failure/insufficiency and the results of caloric extra and limit. The 3rd part bargains an replace at the physiological results of lengthy amenorrhea brought about surgically or by way of hypothalamic disorder and likewise comprises an unique bankruptcy that focuses exclusively at the influence of race and ethnicity at the occurrence and prognosis of amenorrhea. Amenorrhea: A Case-Based medical advisor brings jointly chapters from popular specialists who supply state of the art, clinically valuable details in a case-based, reader-friendly style. This identify should be a welcome boost to the bookshelves of all clinicians who perform in women’s wellbeing and fitness settings.

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Extra resources for Amenorrhea: A Case-Based, Clinical Guide

Sample text

Li TC, Rogers AW, Dockery P et al (1988) A new method of histologic dating of human endometrium in the luteal phase. Fertil Steril 50:52–60 10. Hey NA, Li TC, Devine PL et al (1995) MUC1 in secretory phase endometrium: expression in precisely dated biopsies and flushings from normal and recurrent miscarriage patients. Hum Reprod 10:2655–2662 11. Church HJ, Vicovac LM, Williams JDL et al (1996) Laminins 2 and 4 are expressed by human decidual cells. Lab Invest 74:21–32 12. Aplin JD, Charlton AK, Ayad S (1988) An immunohistochemical study of human endometrial extracellular matrix during the menstrual cycle and first trimester of pregnancy.

Loss of Vascular Integrity Spiral arterioles are unique to menstruating species. The classic studies conducted more than 50 years ago by Markee demonstrated that steroid (estrogen/progesterone) withdrawal produced severe vasoconstriction of the endometrial spiral arterioles lasting 4–24 h [52]. The vasoconstriction is followed by vasodilatation in these vessels, causing increased blood flow. Ischemic damage induced by the vasoconstriction causes blood to flow out of the vessels to the epithelial surface.

F. Santoro and G. R. S. Taylor is a superficial thin layer with gland necks and dense stroma, while the stratum spongiosum is the deeper part of functionalis composed of glands and loosely arranged stroma. Only the functionalis layer of endometrium is shed with each cycle. The basalis layer contains the progenitor cells that regenerate the functionalis layer in each cycle. Endometrial tissue responds to sex steroid hormones produced in the follicular and luteal phases of the ovarian cycle. The menstrual cycle is divided into proliferative and secretory phases, and cytoarchitectural and molecular differences between the phases reflect endometrial responses to cyclic changes in ovarian hormone exposure.

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